We were investors in portfolio company, Patientsafe Solutions, in 2004. They were just ranked #18 in the Wall Street Journal’s second annual Next Big Thing list of the 50 U.S. venture capital backed companies with the greatest promise to succeed. These are start-ups with potential for technological breakthroughs in health care, mobile communications and business software. To be eligible for consideration, companies must have received an venture capital / equity round of financing in the past three years and be valued at less than $1 billion, as the aim is to identify lesser-known contenders.